Empowering the immune system to detect and attack cancer cells

Our flagship product, PROVENGE, is a unique kind of cancer immunotherapy.

Watch this video to learn how it works.
 

PROVENGE reprograms the body’s own immune cells to detect and attack cancer cells, with little impact to healthy tissue or cells.

Additionally, PROVENGE may enable the immune system to fight prostate cancer cells as they change. This is because cancer cells that have been destroyed release identifying information into the bloodstream, which the immune system is trained to recognize and attack, should prostate cancer cells reappear.

In both clinical and real-world settings, PROVENGE has been proven to increase overall survival.

PROVENGE® (sipuleucel-T)

PROVENGE has been available in the United States since 2010. It is the first and only FDA-approved immunotherapy for the treatment of advanced prostate cancer made from a patient’s own immune cells.

This groundbreaking treatment has been prescribed to more than 30,000 men with advanced prostate cancer, helping many live longer.

For more information, please visit PROVENGE.com US healthcare professionals may visit PROVENGEHCP.com

Scientific Publications

Dendreon aims to stay at the forefront of development, manufacturing, and commercialization of immunotherapies that harness the power of the body’s immune system to help extend patients’ lives.

Clinical Trials

In an effort to help even more patients with prostate cancer, we continue to investigate the potential of PROVENGE (sipuleucel-T). For more information, please visit www.clinicaltrials.gov.

Active, Not Recruiting


P12-1 (PREDICT)

  • An observational study to evaluate characteristics predictive of a positive imaging study for metastatic disease in castrate-resistant prostate cancer (CRPC)
  • To learn more, visit ClinincalTrials.gov.

Complete


P11-3 (STAMP)

  • A randomized, open-label, Phase 2 Trial of sipuleucel-T with concurrent versus sequential administration of abiraterone acetate plus prednisone in men with metastatic castrate resistant prostate cancer (mCRPC)
  • To learn more, visit ClinincalTrials.gov.

P12-2 (STRIDE)

  • A randomized, open-label, Phase 2 trial examining combination therapy with sipuleucel-T and enzalutamide in men with asymptomatic or minimally symptomatic metastatic castrate-resistant prostate cancer (mCRPC).
  • To learn more, visit ClinincalTrials.gov.

P10-3 (PROCEED)

  • A registry of sipuleucel-T in men with advanced prostate cancer (PROCEED) to further evaluate safety and survival associated with sipuleucel-T
  • To learn more, visit ClinincalTrials.gov.
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