 Sipuleucel-T Publications
- Rini BI, Weinberg V, Fong L, Conry S, Hershberg RM, Small EJ.
Combination immunotherapy with prostatic acid phosphatase pulsed antigen-presenting cells (provenge) plus bevacizumab in patients with serologic progression of prostate cancer after definitive local therapy.
Cancer. 2006 Jul 1; 107(1):67-74
PMID: 16736512
- Small EJ, Schellhammer PF, Higano CS, Redfern CH, Nemunaitis JJ, Valone FH, Verjee SS, Jones LA, Hershberg RM.
Placebo-controlled phase 3 trial of immunologic therapy with sipuleucel-T (APC8015) in patients with metastatic, asympotomiatic hormone refractroy prostate cancer.
J Clin Oncol. 2006 Jul 1; 24(19):3089-94
PMID: 16809734
- Burch PA, Croghan GA, Gastineau DA, Jones LA, Kaur JS, Kylstra JW, Richardson RL, Valone FH, Vuk-Pavlovic S.
Immunotherapy (APC8015, Provenge) targeting prostatic acid phosphatase can induce durable remission of metastatic androgen-independent prostate cancer: a Phase 2 trial.
Prostate. 2004 Aug 1; 60(3):197-204
PMID: 15176049
- Laus R, Yang D M, Ruegg C L, Shapero M H, Slagle P H, Small E, Burch P, and Valone F H.
"Dendritic cell immunotherapy of prostate cancer: preclinical models and early clinical experience."
Cancer Research Therapy and Control. 2001 Nov; 1-10.
- Burch PA, Breen JK, Buckner JC, Gastineau DA, Kaur JA, Laus RL, Padley DJ, Peshwa MV, Pitot HC, Richardson RL, Smits BJ, Sopapan P, Strang G, Valone FH, Vuk-Pavlovic S.
Priming tissue-specific cellular immunity in a phase I trial of autologous dendritic cells for prostate cancer.
Clin Cancer Res. 2000 Jun; 6(6):2175-82
PMID: 10873066
- Small EJ, Fratesi P, Reese DM, Strang G, Laus R, Peshwa MV, Valone FH.
Immunotherapy of hormone-refractory prostate cancer with antigen-loaded dendritic cells.
J Clin Oncol. 2000 Dec 1; 18(23):3894-3903
PMID: 11099318
Lapuleucel-T Publications
Park JW, Melisko M, Esserman LJ, Jones LA, Wollan JB, Sims R
Other Publications
- Diegel, ML, Chen, F, Laus, R, Graddis, TJ, & Vidovic, D "MHC class I-restricted presentation of protein antigens without prior intracellular processing," Scand J. Immunol., 58:1-8, 2003.
- Vidovic, D, Graddis, TJ, Stepan, LP, Zaller, DM & Laus, R "Specific stimulation of MHC transgenic mouse T cell hybridomas with xenogeneic APC," Human Immunol. 64:238-244, 2003
- Vidovic, D, Graddis, TJ, Chen, F, Slagle, PH, Diegel, ML, Stepan, L.P. & Laus, R. "Anti-tumor vaccination with HER-2 derived recombinant antigens," Int. J. Cancer 102:660-664, 2002
- Valone F, Small E, MacKenzie M, Burch P, Lacy M, Peshwa MV, Laus R, "Dendritic Cell-Based Treatment of Cancer: Closing in on a Cellular Therapy," The Cancer Journal: 7, S53-S61, 2001.
- Valone F, "Dendritic Cells Proving Key to Prostate Cancer Immunotherapy," Prostate Cancer Research Institute (PCRInsights): 4, 4, 1, 6-9, 15-17, 2001.
- Tsavaler L, Shapero M H, Morkowski S, and Laus R, "Trp-p8 , a Novel Prostate-specific Gene, Is Up-Regulated in Prostate Cancer and Other Malignancies and Shares High Homology with Transient Receptor Potential Channel Proteins",, Cancer Research: 61, 3760-3769, 2001
- Laus R, Graddis TJ, Hakim I, and Vidovic D, "Enhanced major histocompatibility complex class I-dependent presentation of antigens modified with cationic and fusogenic peptides", Nature Biotechnology: 18, 12, 1269-1272, 2000.
- Laport GG, Valone FH, Zimmerman TM, Grinblatt DL, van Vlasselaer P, Still BJ, and Williams SF, "Transplantation with low-density autologous PBSC prepared with BDS60 for women with stage II, III and IV breast cancer", Cytotherapy: 2, 3, 179-185, 2000.
- Shapero MH, Kundu SK, Engleman E, Laus R, Merigan TC, "In vivo persistence of donor cells following adoptive transfer of allogeneic dendritic cells in HIV-infected patients", Cell Transplantation: 3, 307-17, 2000.
- Przepiorka D, Lu J-G, Anderlini P, Korbling M, Donato M, Champlin R, Gee AP, and van Vlasselaer P, "Debulking blood stem cell collections by density gradient centrifugation in a closed-vessel system", Cytotherapy: 1, 2, 111-117, 1999.
- van Vlasselaer P, Hasan S, Strang G, and Palathumpat V, "High yield recovery of CD34 cells from apheresed peripheral blood; a novel, high capacity density gradient centrifugation device", Cancer Research Therapy and Control: 7, 89-95, 1998.
- Peshwa MV, Shi JD, Ruegg C, Laus R and van Schooten Wim CA, "Induction of prostate tumor-specific CD8 cytotoxic T-lymphocytes in vitro using antigen-presenting cells pulsed with prostatic acid phosphatase peptide", The Prostate: 36, 129-138, 1998.
- van Vlasselaer P, Palathumpat VC, Strang G, and Shapero MH, "New approaches in density gradient separation using colloidal silica gradients in the processing of human hermatopoietic progenitor cells", Cell Separation Methods and Applications: 15-41, 1998.
- Kundu SK, Engleman E, Benike C, Shapero MH, Dupuis M, van Schooten WC, Eibl M, and Merigan TC, "A pilot clinical trial of HIV antigen-pulsed allogeneic and autologous dendritic cell therapy in HIV-infected patients", AIDS Res Hum Retroviruses: 14(7), 551-60, 1998.
- Peshwa MV, Benike C, Dupuis M, Kundu SK, Engleman EG, Merigan TC, van Schooten WC, "Generation of primary peptide-specific CD8+ cytotoxic T-lymphocytes in vitro using allogeneic dendritic cells", Cell Transplantation: (1)1-9, 1998.
- Fong L, Ruegg CL, Brockstedt D, Engleman EG, Laus R, "Induction of tissue-specific autoimmune prostatisis with prostatic acid phosphatase immunization: implications for immunotherapy of prostate cancer", J Immunol: 159(7):3113-7, 1997.
- Dupuis M, Peshwa MV, Benike C, Kundu SK, Engleman EG, van Schooten WC, Merigan TC, "Allogeneic dendritic cell induction of HIV-specific cytotoxic T lymphocyte responses from T cells of HIV type 1-infected and uninfected individuals", Aids Res Hum Retroviruses: 1, 13(1):33-9, 1997.
- van Shooten WCA, Strang G, Palathumpat V, "Biological properties of dendritic cells. implications to their use in the treatment of cancer", Molecular Medicine Today: 154-160, 1997.
- Przepiorka D, van Vlasselaer P, Huynh L, Durett A, Agbor P, Lauppe J, Valone FH, Champlin R, Körbling M, "Rapid debulking and CD34 enrichment of filgrastim-mobilized peripheral blood stem cells by semiautomated density gradient centrifugation in a closed system", J Hematotherapy: 5, 497-502, 1996.
- Ruegg CL, Wu HY, Fagnoni FF, Engleman EG, Laus R, "B4B, A novel growth-arrest gene, is expressed by subset of progenitor/pre-B lymphocytes negative for cytoplasmic mu-chain", J Immunol.: 1, 157(1):72-80, 1996.
- Peshwa MV, Page LA, Qian L, Yang D, and van Schooten WCA, "Generation and ex vivo expansion of HTLV-1 specific CD8+ cytotoxic T-lymphocytes for adoptive immunotherapy", Biotechnol. Bioeng.: 50, 529-540,1996.
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